Cisplatin fachinformation pdf
WebMay 13, 2024 · In metastatic breast cancer Abraxane is given on its own every three weeks. The recommended dose is 260 mg per square metre of body surface area (calculated using the patient’s height and weight). In metastatic adenocarcinoma of the pancreas Abraxane is given in 4-week treatment cycles. The recommended dose is 125 mg per square metre … WebDec 6, 2024 · Keytruda as monotherapy is indicated for the treatment of locally advanced or metastatic urothelial carcinoma in adults who are not eligible for cisplatin containing chemotherapy and whose tumours express PD L1 with a combined positive score (CPS) ≥ 10. Head and neck squamous cell carcinoma (HNSCC)
Cisplatin fachinformation pdf
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WebJun 1, 2024 · A phase 2 trial of durvalumab in combination with gemcitabine and cisplatin demonstrated promising efficacy, with an objective response rate of 72% and a median … WebProduct information. Here you can find the valid Summaries of Product Characteristics (SmPCs) as well as Educational Material for all products marketed by medac GmbH. …
WebSep 17, 2024 · Overview. Tecentriq is a medicine for treating the following cancers: • urothelial cancer (cancer of the bladder and urinary system); • non-small cell lung cancer … WebCisplatin is similar to the bifunctional alkylating agents. It covalently binds to DNA and disrupts DNA function. 6. After cisplatin enters the cells, the chloride ligands are replaced by water molecules. 7,8. This reaction results in the formation of positively charged platinum complexes that react with the nucleophilic sites on DNA. 2. These ...
WebMay 30, 2024 · Branded. We supply branded generics and in-licensed patented products from our local manufacturing facilities to retail and hospital customers across the MENA region. Generics. We supply oral and other non‑injectable generic and specialty products to the US retail market, leveraging our state-of-theart manufacturing facility in Columbus, … WebSep 27, 2024 · Cisplatin for injection, USP: single-dose vials containing 50 mg of cisplatin as white to light yellow lyophilized powder for reconstitution. 4 CONTRAINDICATIONS Cisplatin for injection is contraindicated in patients with severe hypersensitivity to cisplatin [see Warnings and Precautions (5.4)]. 5 WARNINGS AND PRECAUTIONS
WebSep 1, 2024 · Cisplatin for injection is indicated for the treatment of advanced testicular cancer. Advanced Ovarian Cancer Cisplatin for injection is indicated for the treatment of advanced ovarian cancer. Advanced Bladder Cancer Cisplatin for injection is indicated for the treatment of advanced bladder cancer. Related/similar drugs
WebMaterial Name: Cisplatin Injection Trade Name: Not applicable Chemical Family: Mixture Intended Use: Pharmaceutical product used as Antineoplastic 2. HAZARDS … scottish papers newsWeb(carboplatin) or prescribing practices that fail to differentiate daily doses from total dose per cycle. DESCRIPTION PLATINOL (cisplatin for injection, USP) is a white to light yellow lyophilized... scottish paperweights for saleWebA document describing the properties and the officially approved conditions of use of a medicine. Summaries of product characteristics form the basis of information for healthcare professionals on how to use the medicine safely and effectively. Abbreviated as SmPC. preschool exercise cardsWebJan 1, 2015 · Die Verteilung von Cisplatin zeigt besonders hohe Konzentrationen in Nieren, Leber, Gonaden, Milz, Prostata, Harnblase, Pankreas, Muskulatur und Nebennieren und kann dort bis zu 2–4 Wochen persistieren. Die Aufnahme ins ZNS und in den Liquor cerebrospinalis ist gering. preschool everythingWebJul 22, 2024 · Cellular toxicity — Cisplatin (cis-diamminedichloroplatinum II [CDDP]), a platinum compound that is predominantly eliminated through renal clearance. Inside cells, the low chloride concentration facilitates CDDP … scottish parliamentary election resultsWebCisplatin is similar to the bifunctional alkylating agents. It covalently binds to DNA and disrupts DNA function. 6. After cisplatin enters the cells, the chloride ligands are … preschool examWebCisplatin Injection is indicated as a single agent for patients with transitional cell bladder cancer which is no longer amenable to local treatments, such as surgery and/or r … preschool explorers